The aim of the CRIM-TRACK project is to demonstrate a working sensing device that can be developed into a portable, miniaturized, automated, rapid, low cost, highly sensitive, and simple “sniffer” and detection unit, based on a disposable micro-colorimetric chip. The unit can be used for identification of a wide variety of illegal drugs, drug precursors and home-made explosives. The project combines highly advanced disciplines, like organic chemistry, micro fabrication and hardware technology, machine learning and signal processing techniques. It will provide custom officers, police and other authorities with an effective tool to control trafficking of illegal drugs and drug precursors.